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Mapping protein-DNA interactions in chromatin using CUT&RUN

Mapping protein-DNA interactions in chromatin using CUT&RUN

Learn about CUT&RUN from Cell Signaling Technology® (CST) – a low cell number alternative to ChIP-qPCR and ChIP-seq to analyze protein-DNA interaction in chromatin.   What is CUT&RUN? The development of methods that enable mapping of protein-DNA...
Customized depletion of abundant RNAs

Customized depletion of abundant RNAs

RNA-sequencing (RNA-Seq) is a high-throughput sequencing method that facilitates the study of the entire transcriptome. However, revealing the presence and quantity of the RNAs of interest in a biological sample can be difficult due to the abundance of highly...
Nucleic acid staining – Dyes & Transilluminators

Nucleic acid staining – Dyes & Transilluminators

Different fluorescent compounds can intercalate nucleic acid chains, both single and double-stranded. Ethidium bromide (EtBr) is likely the most well-known DNA dye. However, reports on EtBr carcinogenicity and mutagenicity have potentiated the development of safer...
A50 the antibody for detection of SARS-COV-2

A50 the antibody for detection of SARS-COV-2

Rockland Immunochemicals Inc.´s anti-SARS-CoV Nucleocapsid (N) Protein (RABBIT) Antibody (200-401-A50) is a critical reagent for detection of SARS-CoV-2 in a variety of different immunoassays. This reagent can be applied to diagnostic testing for presence of Covid 19...
An Enzyme for Innovation

An Enzyme for Innovation

Tth Argonaute (TtAgo)- The first programmable, ssDNA-dependent Endonuclease.   Tth Argonaute (TtAgo) is a new and exciting prokaryotic enzyme that may open up your mind to new ideas.  RNA interference has been widely described in eukaryotes involving small...
FRUSTRATION with your LIGATION?

FRUSTRATION with your LIGATION?

DNA ligation is a commonly used method in molecular cloning to physically join vector DNA to a gene of interest. It is a relative straightforward technique which involves mixing of DNA insert and vector DNA together with a DNA ligase followed by incubation, heat...